Vulvar Cancer in the North of Israel
Identifieur interne : 002315 ( Main/Exploration ); précédent : 002314; suivant : 002316Vulvar Cancer in the North of Israel
Auteurs : Orit Kaidar-Person [Israël] ; Nour Ibrahim [Israël] ; Amnon Amit [Israël] ; Roxolyana Bortnyak-Abdah [Israël]Source :
- Rambam Maimonides Medical Journal [ 2076-9172 ] ; 2014.
Abstract
This is a population study of patients who were treated for vulvar cancer in a tertiary center in northern Israel, aimed to report clinical findings, treatment, and outcome.
A retrospective chart review of all medical records of consecutive patients who were treated for vulvar cancer in the years 1993–2012 was conducted. Data extracted from the medical records included demographics, histology, size of lesion, stage of disease at diagnosis, type of treatment, radiation dose, follow-up, recurrence, and survival.
The study included 44 patients with a median age of 69.8 years (range, 42–93 years). Thirty-five (79.5%) of the patients were of Jewish descent, five were Arabic, and four were of other descent. The most common histology type was squamous cell carcinoma in 35 (79.5%) patients. Most patients were staged FIGO II–III at time of diagnosis. Surgery was the most common primary treatment modality (54.2%). Twenty-three (52.2%) patients had recurrent disease. Older age and more advanced stage at diagnosis were associated with increased mortality.
Vulvar cancer is common among elderly women with co-morbidities who present in advanced disease stage; all these factors are significant for survival.
Url:
DOI: 10.5041/RMMJ.10156
PubMed: 25120922
PubMed Central: 4128593
Affiliations:
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Oncology, Rambam Health Care Campus, Haifa, Israel</nlm:aff><country xml:lang="fr">Israël</country><wicri:regionArea>Division of Oncology, Rambam Health Care Campus, Haifa</wicri:regionArea><wicri:noRegion>Haifa</wicri:noRegion></affiliation></author><author><name sortKey="Amit, Amnon" sort="Amit, Amnon" uniqKey="Amit A" first="Amnon" last="Amit">Amnon Amit</name><affiliation wicri:level="1"><nlm:aff id="af2-rmmj-5-3-e0022">Gyneco-Oncology Unit, Rambam Health Care Campus, Haifa, Israel</nlm:aff><country xml:lang="fr">Israël</country><wicri:regionArea>Gyneco-Oncology Unit, Rambam Health Care Campus, Haifa</wicri:regionArea><wicri:noRegion>Haifa</wicri:noRegion></affiliation></author><author><name sortKey="Bortnyak Abdah, Roxolyana" sort="Bortnyak Abdah, Roxolyana" uniqKey="Bortnyak Abdah R" first="Roxolyana" last="Bortnyak-Abdah">Roxolyana Bortnyak-Abdah</name><affiliation wicri:level="1"><nlm:aff wicri:cut=" and" id="af1-rmmj-5-3-e0022">Division of Oncology, Rambam Health Care Campus, Haifa, Israel</nlm:aff><country xml:lang="fr">Israël</country><wicri:regionArea>Division of Oncology, Rambam Health Care Campus, Haifa</wicri:regionArea><wicri:noRegion>Haifa</wicri:noRegion></affiliation></author></analytic><series><title level="j">Rambam Maimonides Medical Journal</title><idno type="eISSN">2076-9172</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Purpose</title><p>This is a population study of patients who were treated for vulvar cancer in a tertiary center in northern Israel, aimed to report clinical findings, treatment, and outcome.</p></sec><sec><title>Methods</title><p>A retrospective chart review of all medical records of consecutive patients who were treated for vulvar cancer in the years 1993–2012 was conducted. Data extracted from the medical records included demographics, histology, size of lesion, stage of disease at diagnosis, type of treatment, radiation dose, follow-up, recurrence, and survival.</p></sec><sec><title>Results</title><p>The study included 44 patients with a median age of 69.8 years (range, 42–93 years). Thirty-five (79.5%) of the patients were of Jewish descent, five were Arabic, and four were of other descent. The most common histology type was squamous cell carcinoma in 35 (79.5%) patients. Most patients were staged FIGO II–III at time of diagnosis. Surgery was the most common primary treatment modality (54.2%). Twenty-three (52.2%) patients had recurrent disease. Older age and more advanced stage at diagnosis were associated with increased mortality.</p></sec><sec><title>Conclusion</title><p>Vulvar cancer is common among elderly women with co-morbidities who present in advanced disease stage; all these factors are significant for survival.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Bodelon, C" uniqKey="Bodelon C">C Bodelon</name></author><author><name sortKey="Madeleine, Mm" uniqKey="Madeleine M">MM Madeleine</name></author><author><name sortKey="Voigt, Lf" uniqKey="Voigt L">LF Voigt</name></author><author><name sortKey="Weiss, Ns" uniqKey="Weiss N">NS Weiss</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aragona, Am" uniqKey="Aragona A">AM Aragona</name></author><author><name sortKey="Cuneo, Na" uniqKey="Cuneo N">NA Cuneo</name></author><author><name sortKey="Soderini, Ah" uniqKey="Soderini A">AH Soderini</name></author><author><name sortKey="Alcoba, Eb" uniqKey="Alcoba E">EB Alcoba</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garland, Sm" uniqKey="Garland S">SM Garland</name></author><author><name sortKey="Insinga, Rp" uniqKey="Insinga R">RP Insinga</name></author><author><name sortKey="Sings, Hl" uniqKey="Sings H">HL Sings</name></author><author><name sortKey="Haupt, Rm" uniqKey="Haupt R">RM Haupt</name></author><author><name sortKey="Joura, Ea" uniqKey="Joura E">EA Joura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dittmer, C" uniqKey="Dittmer C">C Dittmer</name></author><author><name sortKey="Katalinic, A" uniqKey="Katalinic A">A Katalinic</name></author><author><name sortKey="Mundhenke, C" uniqKey="Mundhenke C">C Mundhenke</name></author><author><name sortKey="Thill, M" uniqKey="Thill M">M Thill</name></author><author><name sortKey="Fischer, D" uniqKey="Fischer D">D Fischer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dittmer, C" uniqKey="Dittmer C">C Dittmer</name></author><author><name sortKey="Fischer, D" uniqKey="Fischer D">D Fischer</name></author><author><name sortKey="Diedrich, K" uniqKey="Diedrich K">K Diedrich</name></author><author><name sortKey="Thill, M" uniqKey="Thill M">M Thill</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Piura, B" uniqKey="Piura B">B Piura</name></author><author><name sortKey="Rabinovich, A" uniqKey="Rabinovich A">A Rabinovich</name></author><author><name sortKey="Cohen, Y" uniqKey="Cohen Y">Y Cohen</name></author><author><name sortKey="Friger, M" uniqKey="Friger M">M Friger</name></author><author><name sortKey="Glezerman, M" uniqKey="Glezerman M">M Glezerman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Beckmann, Am" uniqKey="Beckmann A">AM Beckmann</name></author><author><name sortKey="Kiviat, Nb" uniqKey="Kiviat N">NB Kiviat</name></author><author><name sortKey="Daling, Jr" uniqKey="Daling J">JR Daling</name></author><author><name sortKey="Sherman, Kj" uniqKey="Sherman K">KJ Sherman</name></author><author><name sortKey="Mcdougall, Jk" uniqKey="Mcdougall J">JK McDougall</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sorrentino, Mf" uniqKey="Sorrentino M">MF Sorrentino</name></author><author><name sortKey="Kim, J" uniqKey="Kim J">J Kim</name></author><author><name sortKey="Foderaro, Ae" uniqKey="Foderaro A">AE Foderaro</name></author><author><name sortKey="Truesdell, Ag" uniqKey="Truesdell A">AG Truesdell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moore, Dh" uniqKey="Moore D">DH Moore</name></author><author><name sortKey="Ali, S" uniqKey="Ali S">S Ali</name></author><author><name sortKey="Koh, Wj" uniqKey="Koh W">WJ Koh</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Israël</li></country></list><tree><country name="Israël"><noRegion><name sortKey="Kaidar Person, Orit" sort="Kaidar Person, Orit" uniqKey="Kaidar Person O" first="Orit" last="Kaidar-Person">Orit Kaidar-Person</name></noRegion><name sortKey="Amit, Amnon" sort="Amit, Amnon" uniqKey="Amit A" first="Amnon" last="Amit">Amnon Amit</name><name sortKey="Bortnyak Abdah, Roxolyana" sort="Bortnyak Abdah, Roxolyana" uniqKey="Bortnyak Abdah R" first="Roxolyana" last="Bortnyak-Abdah">Roxolyana Bortnyak-Abdah</name><name sortKey="Ibrahim, Nour" sort="Ibrahim, Nour" uniqKey="Ibrahim N" first="Nour" last="Ibrahim">Nour Ibrahim</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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